White-tailed deer in the agricultural Midwest are limited during fall and winter to areas of combined food and cover, usually remnant forests in a matrix of agriculture. During this period, tree seedlings may be at higher risk to herbivory because herbaceous and agricultural foods are unavailable and deer are concentrated in forest patches. We monitored planted swamp white oak seedlings to examine how autumnal herbivory affected nutrient loss and survival. Herbivory during this season resulted in significant losses of nitrogen and phosphorous stored within the stem, with nitrogen stores significantly reduced throughout the seedling's tissues. Nutrient loss due to deer herbivory has the potential to prevent seedlings from reaching reproductive maturity, altering future successional paths and affecting forest composition. To alleviate herbivory pressure, forested refuges may benefit from hunting or sharpshooting, with treatments coinciding with peak crop harvest activity.